PsoriaLess® - natural bio active solutions in dry, scaly skins
This blog is about psoriasis, eczema and scaly skins in general. We try to publish as much as possible information on the treatment of scaly skins, psoriasis, eczema etc. For decades we promote the use of 100% natural based on vegetal, ingredients from plants, that are safe and effective in the treatment of scaly skins such as psoriasis, scalp psoriasis, eczema, dermatitis, (severe) dandruff etc. We are here to help you. Please feel free to submit any information that you may find useful for our readers in their treatment process. Should you require any help or support, please do not hesitate to contact us here Natural skin care works to safely support the health of your skin.
Pitting, yellow-brown discoloration and deformation of finger and toe nails are common; 51.8% of patients suffered from pain-caused by the nail changes, and a large group of patients was restricted in their daily activities, housekeeping and/or profession.
Two of the three major pathogenic features of psoriasis–abnormal keratinocyte differentiation and hyperproliferation of keratinocytes are abnormalities of growth and maturation of skin cells. We think the growth disturbances are secondary to an immune cell infiltration of the skin and the release of immune mediators (cytokines) which promote cell growth and inflammation at the same time. Evidence suggests that T-lymphocytes lead the attack on the skin. Although psoriatic plaques tend to be good breeding grounds for bacteria and fungi, there is no proof that infection is the cause of the problem.
Psoriasis is a complex disorder involving immune attacks in skin with chronic inflammation and exuberant overgrowth of the upper layers of skin. Psoriatic plaques are covered with thick silvery scales which shed at an alarming rate – super dandruff. The disease usually involves the extensor surfaces of the body – the opposite to eczema which prefers the flexor surfaces. Psoriasis tend to be a chronic disease lasting years to decades and in some patients follows and erratic course – flaring and subsiding in cycles lasting many months.
Psoriasis affects 1.5 % to 2.0 % of the population in western countries with equal incidence in males and females. There is genetic tendency: when one parent has psoriasis, 8 % of offspring develop psoriasis, and when both parents have psoriasis, 41 % develop psoriasis. Class I antigens associated with psoriasis are: HLA-B13, -B17, -Bw57, -CW6.
Little progress has been made in understanding and treating Psoriasis – it is one of the many immune-mediated diseases that rage-on unchecked. Medical treatments have not been very helpful and for many years psoriasis has been a target of dubious marketing practices – none of numerous creams and lotions offered to treat the disease have been efficacious. Coal tar derivatives and peeling agents have been the most plausible treatments but offer little relief. Even the steroids – the all purpose drugs for skin disorders – are disappointing .
They Suffer Socially…
People with extensive psoriasis tend to suffer socially and are often unwilling to bare their body in public – swimming pools and beaches are of limits for some because of embarrassment about the skin lesions which do look rather menacing to onlookers who are not familiar with the disease. Swimming in salt water and sun exposure is often helpful, however, and ultraviolet light treatment has been used as a standard therapy. For years people have been treated with coal tar baths followed by ultraviolet light exposure with benefits. Now, of course, we are warning people against ultraviolet light exposure and have concerns about the carcinogenic potential of coal tar.
Psoriatic arthritis occurs in 5 % to 8 % of patients with psoriasis. There are two types:
- Mild, single joints – involving, asymmetrically, a few distal interphalangeal joints of the hands and feet:
- Aggressive psoriatic arthritis with bone erosion and ankylosis involving the sacroiliac, hip, and cervical areas with ankylosing spondylitis; seen especially in erythrodermic and pustular psoriasis.